Extrahepatic Portal Vein Obstruction (EHPVO) and Non-Cirrhotic Portal Fibrosis (NCPF) are important causes of portal hypertension in children and young adults. Unlike cirrhosis-related portal hypertension, these conditions affect patients with preserved liver function but can still lead to life-threatening complications such as variceal bleeding, splenomegaly, and hypersplenism. At KD Hospital, under the care of Dr. V. Y. Bhargav, patients with EHPVO/NCPF receive specialized evaluation, monitoring, and long-term management to prevent complications and improve quality of life.
EHPVO results from obstruction or thrombosis of the portal vein outside the liver, often due to clotting disorders, infections, or congenital anomalies. NCPF is a chronic condition characterized by fibrosis around the portal tracts without cirrhosis, leading to portal hypertension. Both conditions commonly present with upper gastrointestinal bleeding from esophageal or gastric varices, splenomegaly, and low blood counts due to hypersplenism.